Most recent publications:

Up to date publication list (Google Scholar)

  1. In-Cell Fast Photochemical Oxidation Interrogates the Native Structure of Integral Membrane Proteins, Jie Sun, Mierxiati Saimi, Don Rempel, Qing Cao, Mengqi Chai, Weikai Li and Michael L. Gross, Angewandte Chemie, e202424779, (2025).
  2. Kingfisher: An open-sourced web-based platform for the analysis of hydrogen exchange mass spectrometry data, Nolan K. McLaughlin, Juan P. Rincon Pabon, Samantha Gies, Reza Dastvan and Michael L. Gross, Protein Science, 34, e70096, (2025).
  3. Molecular basis for human respiratory syncytial virus transcriptional regulator NS1 interactions with MED25, Parismita Kalita, Oam Khatavkar, Grace Uwase, Yulia Korshunova, Yuying Hu, Nicole D. Wagner, Jian Xu, Jiehong Pan, Jay C. Nix, Michael L. Gross, Steven L. Brody, Dominika Borek, Gaya K. Amarasinghe, Jacqueline E. Payton and Daisy W. Leung, Nature Communication, 16, 2883, (2025).
  4. Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface, Qing Cao, Aaron Ammerman, Mierxiati Saimi, Zongtao Lin, Guomin Shen, Huaping Chen, Jie Sun, Mengqi Chai, Shixuan Liu, Fong-Fu Hsu, Andrzej M. Krezel, Michael L. Gross, Jinbin Xu, Benjamin A. Garcia, Bin Liu and Weikai Li, Nature, 639, 816-824, (2025).
  5. Mass Spectrometry-Based Protein Footprinting for Protein Structure Characterization, Ming Cheng and Michael L. Gross, Accounts of Chemical Research, 58, 165-176, (2025).
  6. Distinguishing Isomeric Cyclobutane Thymidine Dimers by Ion Mobility and Tandem Mass Spectrometry, Hsin-Chieh Yang, Savannah S. Scruggs, Mengqi Chai, George Mathai, John-Stephen Taylor and Michael L. Gross, J Am Soc Mass Spectrom, 35, 1768-1774, (2024).
  7. Using mass spectrometry-based methods to understand amyloid formation and inhibition of alpha-synuclein and amyloid beta, Wesley J. Wagner and Michael L. Gross, Mass Spectrom Rev, 43, 782-825, (2024).
  8. Evaluating Chemical Footprinting-Induced Perturbation of Protein High Order Structure, Wesley Wagner, Austin Moyle, Nicole Wagner, Don Rempel, Michael L. Gross, Analytical Chemistry, 96, 9693-9703 (2024)
  9. An exploration of Resveratrol as a potent modulator of α-synuclein fibril formation, Eva Illes-Toth, Don L Rempel, Michael L Gross, ACS Chemical Neuroscience, 15, 503-516 (2024).
  10. Using Mass Spectrometry-Based Methods to Understand the Amyloid Formation and Inhibition of Alpha-Synuclein and Amyloid Beta, Wesley J. Wagner and Michael L. Gross, Mass Spectrometry Reviews, 43: 782–825 (2024).
  11. Development of a High-throughput Mass Spectrometry-based Sars-Cov-2 Immunoassay, Jie Sun, Jong Hee Song, Mary Danielson, Nathan Colley, Alia Thomas, David Hambly, Jonathan Barnes, Michael L. Gross, Analytical Chemistry, 96, 12-17 (2024).
  12. A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection, Lucas J. Adams, Laura A. VanBlargan, Zhuoming Liu, Pavlo Gilchuk, Haiyan Zhao, Rita E. Chen, Saravanan Raju, Zhenlu Chong, Bradley M. Whitener, Swathi Shrihari, Prashant N. Jethva, Michael L. Gross, James E. Crowe, Jr., Sean P.J. Whelan, Michael S. Diamond, and Daved H. Fremont, Cell Reports Medicine, 4,101305 (2023).
  13. Antibody Binding Captures High Energy State of an Antigen: The Case of Nsp1 SARS-CoV-2 as Revealed by Hydrogen–Deuterium Exchange Mass Spectrometry, Ravi Kant, Nawneet Mishra, and Michael L Gross,  J. Mol. Sci.,24, 17342. Precursor Reagent Hydrophobicity Affects Membrane Protein Footprinting, Chunyang Guo, Ming Cheng, Weikai Li, Michael L. Gross, J. Am. Soc. Mass Spectrom., 34, 2700-2710 (2023).
  14. Characterization of Higher Order Structural Changes of a Thermally Stressed Monoclonal Antibody via Mass Spectrometry Footprinting and Other Biophysical Approaches, Yanchun Lin, Austin B. Moyle, Victor A. Beaumont, Lucy L. Liu, Sharon Polleck, Haijun Liu, Heliang Shi, Jason C. Rouse, Hai-Young Kim, Ying Zhang, Michael L. Gross,  Chem., 95,16840-16849 (2023).
  15. The intricacies of Ebola NP0VP35 formation of inclusion body-like structures and their disruption reducing viral infection, Chao Wu, Nicole Wagner, Austin B. Moyle, Annie Feng, Nitin Sharma, Sarah H. Stubbs, Callie Donahue, Robert Davey, Michael L. Gross, Daisy W. Leung, and Gaya K. Amarasinghe, Journal of Molecular Biology, 435, 168241 (2023).
  16. A Workflow for Validating Specific Amino Acid Footprinting Reagents for Protein HOS Elucidation, Austin B. Moyle, Nicole D. Wagner, Wesley J. Wagner, Ming Cheng, Michael L. Gross,  Chem.,95, 10119-10126 (2023).
  17. Biochemical and HDX mass spectral characterization of the SARS-CoV-2 Nsp1 protein, Nawneet Mishraa, Ravi Kant, Daisy W. Leung, Michael L. Gross, and Gaya K. Amarasinghe, Biochemistry, 62, 1744-1754 (2023).
  18. Hydrogen Deuterium Exchange and other Mass Spectrometry-based Approaches for Epitope Mapping, Prashant N. Jethva and Michael L Gross, (Invited Review) Frontiers Anal. Sci.Volume 3 (2023).
  19. Antigenic landscapes on Staphylococcus aureuspore-forming toxins reveal insights into specificity and cross-neutralization, Shweta Kailasan, Ravi Kant, Madeleine Noonan-Shueh, Tulasikumari Kanipakala, Grant Liao, Sergey Shulenin, Daisy W. Leung, Richard A. Alm, Rajan P. Adhikaria, Gaya K. Amarasinghe, Michael L. Gross, and M. Javad Aman, mAbs, 14, e2083467: 1-17, (2022).
  20. Advances in Mass Spectrometry-Based Footprinting of Membrane Proteins (invited review), Jie Sun, Weikai Li, and Michael L. Gross, Proteomics, 22, e2100222 (2022)
  21. Isolation of a potently neutralizing and protective human monoclonal antibody targeting yellow fever virus, Michael P. Doyle, Joseph R. Genualdi, Adam L. Bailey, Nurgun Kose, Christopher Gainza, Jessica Rodriguez, Kristen M. Reeder, Christopher A. Nelson, Prashant N. Jethva, Rachel E. Sutton, Robin G. Bombardi, Michael L. Gross, Justin G. Julander, Daved H. Fremont Michael S. Diamond, James E. Crowe Jr.  Mbio, e00512-22 (2022).
  22. Benzoyl Transfer for Footprinting Alcohol-Containing Residues in Higher Order Structural Applications of Mass-Spectrometry-Based Proteomics, Austin B. Moyle, Ming Cheng, Nicole D. Wagner, Michael L. Gross,  Chem.94, 1520-1524 (2022).
  23. Nipah Virus V Protein Binding Alters MDA5 Helicase Folding Dynamics, Nicole Wagner, Hejun Liu, Henry Rohrs, Gaya Amarasinghe, Michael L Gross, Daisy Leung, ACS Infectious Diseases, ACS Infect. Dis., 8, 118−128 (2022).
  24. Nanoparticles and Photochemistry for Native-like Transmembrane Protein Footprinting Nanoparticles and Photochemistry for Native-like Transmembrane Protein Footprinting, Jie Sun, Xiaoran Roger Liu, Shuang Li, Peng He, Weikai Li, and Michael L. Gross, Nature Commun,12, 7270 (2021).
  25. Diethylpyrocarbonate Footprints a Membrane Protein in Micelles, Chunyang Guo, Ming Cheng, Weikai Li, Michael L. Gross,  Amer. Soc. Mass Spectrom., 32, 2636-2643 (2021).
  26. Carbocation Footprinting of Soluble and Transmembrane Proteins, Jie Sun, Shuang Li, Weikai Li, and Michael L. Gross, Anal. Chem., 93,13101-13105 (2021).
  27. Footprinting Mass Spectrometry of Membrane Proteins: Ferroportin Reconstituted in Saposin A Picodiscs, Fengbo Zhou, Yihu Yang, Saketh Chemuru, Weidong Cui, Shixuan Liu, Michael Gross, and Weikai Li,  Chem., 93, 11370–11378 (2021).
  28. Pan-protective anti-alphavirus human antibodiestarget a conserved E1 protein epitope, Arthur S. Kim, Natasha M. Kafai, Emma S. Winkler, Theron C. Gilliland, Jr., Emily L. Cottle, James T. Earnest, Prashant N. Jethva, Paulina Kaplonek, Aadit P. Shah, Rachel H. Fong, Edgar Davidson, Ryan J. Malonis, Jose A. Quiroz, Lauren E. Williamson, Lo Vang, Matthias Mack, James E. Crowe, Jr., Benjamin J. Doranz, Jonathan R. Lai, Galit Alter, Michael L. Gross, William B. Klimstra, Daved H. Fremont, Michael Diamond, Cell,184, 414-4429 (2021).
  29. Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain, Chao Wu, Abraham J Qavi, Asamaa Hachim, Niloufar Kavian, Aidan R Cole, Austin B Moyle, Nicole D Wagner, Joyce Sweeney-Gibbons, Henry W Rohrs, Michael L Gross, J S Malik Peiris, Christopher F Basler, Christopher W Farnsworth, Sophie A Valkenburg, Gaya K Amarasinghe, Daisy W Leung, iScience 24, 102681 (2021).
  30. Native Mass Spectrometry and Gas-phase Fragmentation Provide Rapid and In-depth Topological Characterization of a PROTAC Ternary Complex, Jong Hee Song, Nicole D. Wagner, Jing Yan, Jing Li, Richard Y.-C. Huang, Aaron J. Balog, John A. Newitt, Guodong Chen, and Michael L. Gross, Cell Chemical Biology, 28, 1528-1538 (2021).
  31. Pulsed Hydrogen−Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer’s Disease Mutants, Eva Illes-Toth, Georg Meisl, Don L. Rempel, Tuomas P. J. Knowles, and Michael L. Gross, ACS Chemical Neuroscience, 12,1972-1982 (2021).
  32. Free-Radical Membrane Protein Footprinting by Photolysis of Perfluoroisopropyl Iodide Partitioned to Detergent Micelle by Sonication, Ming Cheng, Chunyang Guo, Weikai Li, and Michael L Gross, Angewandte Chemie, Int Ed Engl, 16, 8867-8873 (2021).
  33. Protein higher-order-structure determination by fast photochemical oxidation of proteins and mass spectrometry analysis. Xiaoran Roger Liu, Don L Rempel, and Michael L. Gross, Nature Protocols, 15, 3942-3970 (2020). 
  34. Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane, Ben Niu (…),  Michael L. Gross (…), and Andrew G. Stephen, Proceedings of the National Academy of Sciences of the USA, 117, 24258-24268 (2020).
  35. Calcium Binding to the Innate Immune Protein Human Calprotectin Revealed by Integrated Mass Spectrometry, Jagat Adhikari, Jules R. Stephan, Don L. Rempel, Elizabeth M. Nolan, and Michael L. Gross,  Am. Chem. Soc., 142, 31, 13372–13383 (2020).
  36. Fast Protein Footprinting by X-ray Mediated Radical Trifluoromethylation, Ming Cheng, Awuri Asuru, Janna Kiselar, George Mathai, Mark R. Chance, and Michael L. Gross,  Amer. Soc. Mass Spectrom., 31,1019-1024 (2020).
  37. Site-Specific Siderocalin Binding to Ferric and Ferric-Free Enterobactin as Revealed by Mass Spectrometry, Chunyang Guo, Lindsey K. Steinberg, Ming Cheng, Jong Hee Song, Jeffrey P. Henderson, Michael L. Gross, ACS Chemical Biology, 15, 1154-1160 (2020).
  38. Mass Spectrometry-Based Protein Footprinting for Higher Order Structure Analysis: Fundamentals and Applications, Xiaoran Roger Liu, Mengru Mira Zhang, and Michael L. Gross, Chemical Reviews, 120, 10, 4355-4454 (2020).
  39. The Cap-Snatching SFTSV Endonuclease Domain is an Antiviral Target, Wenjie Wang, Woo Jin Shin, Bojie Zhang, Younho Choi, Ji Seung Yoo, Maxwell I. Zimmerman, Thomas E. Frederick, Gregory R. Bowman, Michael L. Gross, Daisy W. Leung, Jae U. Jung, Gaya K. Amarasinghe, Cell Reports, 30,153-163.e5 (2020).
  40. The Application of Fluorine‐Containing Reagents in Structural Proteomics, Ming Cheng, Chunyang Guo, and Michael L. Gross,Angewandte Chemie-International Edition, 59, 5880-5889 (2020).
  41. Protein Footprinting and X-ray Crystallography Reveal the Interaction of PD-L1 and a Macrocyclic Peptide, Ben Niu, Todd C. Appleby, Ruth Wang, Mariya Morar, Johannes Voight, Armando G. Villaseñor, Sheila Clancy, Sarah Wise, Jean-Philippe Belzile, Giuseppe Papalia, Melanie Wong, Katherine M. Brendza, Latesh Lad, and Michael L. Gross, Biochemistry, 59,541-551 (2020).

 

 

 

 

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